CD7 is a cell membrane glycoprotein with a molecular weight of 40kDa. It is an early T cell and NK cell antigen. It is expressed on most T cells and natural killer cells and belongs to the immunoglobulin super gene family. CD7 is mainly used for the classification of T lymphocyte lymphoma and leukemia. CD7 is expressed in 85% of peripheral T cells, NK cells, myeloid cells, T cell acute lymphoblastic leukemia/lymphoma, acute myeloid leukemia and chronic myeloid leukemia. This product is a CD7- FC recombinant protein (FC tag can be removed by enterokinase), which can be used for monoclonal antibody screening or antibody function verification.

Product name: Recombinant human CD7 protein

Species: Human origin

Gene sequence number: P09564

Tags: Human-Fc Tag

Tag site: C terminal

Restriction site: enterokinase

Expression area: extracellular segment 26-180AA

Host cell:CHO

Purity: ＞90%

Purification method: Protein A column

Preservation system: PBS+20% glycerol

Storage conditions: -80℃

Picture : Lane M on the left is the protein MW marker, Lane 1 is 15ug CD7-Fc protein;

The right picture shows the flow cytometric detection of CD7-Fc protein binding to 293T overexpressing CD7-CAR

Reference test data:

1. Characterization of the surface topography and putative tertiary structure of the human CD7 molecule

2. Assignment of a gene coding for a human T-cell antigen with a molecular weight of 40,000 daltons to chromosome 17

3. Molecular cloning of two CD7 (T-cell leukemia antigen) cDNAs by a COS cell expression system